Jennifer e symonds (32 Ergebnisse)

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Paperback. Zustand: New. SCN2A encodes a voltage-gated sodium channel (designated NaV1.2) vital for generating neuronal action potentials. Pathogenic SCN2A variants are associated with a diverse array of neurodevelopmental disorders featuring neonatal or infantile onset epilepsy, developmental delay, autism, intellectual disability and movement disorders. SCN2A is a high confidence risk gene for autism spectrum disorder and a commonly discovered cause of neonatal onset epilepsy. This remarkable clinical heterogeneity is mirrored by extensive allelic heterogeneity and complex genotype-phenotype relationships partially explained by divergent functional consequences of pathogenic variants. Emerging therapeutic strategies targeted to specific patterns of NaV1.2 dysfunction offer hope to improving the lives of individuals affected by SCN2A-related disorders. This Element provides a review of the clinical features, genetic basis, pathophysiology, pharmacology and treatment of these genetic conditions authored by leading experts in the field and accompanied by perspectives shared by affected families. This title is also available as Open Access on Cambridge Core.…

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PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

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Zustand: New. In English.

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Paperback. Zustand: Brand New. 544 pages. 9.00x6.00x1.25 inches. In Stock.

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Paperback. Zustand: New. SCN2A encodes a voltage-gated sodium channel (designated NaV1.2) vital for generating neuronal action potentials. Pathogenic SCN2A variants are associated with a diverse array of neurodevelopmental disorders featuring neonatal or infantile onset epilepsy, developmental delay, autism, intellectual disability and movement disorders. SCN2A is a high confidence risk gene for autism spectrum disorder and a commonly discovered cause of neonatal onset epilepsy. This remarkable clinical heterogeneity is mirrored by extensive allelic heterogeneity and complex genotype-phenotype relationships partially explained by divergent functional consequences of pathogenic variants. Emerging therapeutic strategies targeted to specific patterns of NaV1.2 dysfunction offer hope to improving the lives of individuals affected by SCN2A-related disorders. This Element provides a review of the clinical features, genetic basis, pathophysiology, pharmacology and treatment of these genetic conditions authored by leading experts in the field and accompanied by perspectives shared by affected families. This title is also available as Open Access on Cambridge Core.…

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Paperback. Zustand: new. Paperback. The school-to-work transition is a critical part of the human life-span for young adults, their families, and society. The timing of the transition varies greatly and its co-occurrence with a number of other life transitions make it challenging to summarize or generalize. Individual differences and normative developmental factors, as well as external contextual factors such as global pandemics, changing economic circumstances, workplace demands, and cultural shifts,intersect to create a range of challenges and opportunities for those navigating this transition.Written by internationally renowned scholars in developmental psychology,applied psychology, counseling, and sociology, the chapters in this book highlight the trends, issues, and actions that researchers, academics, practitioners, and policy makers need to consider in order to effectively support young adults' transition to work pathways. This volume provides an explicitly international perspective on this area, broad coverage of psychological topics on the school-to-work transition, and an inclusive focus on sub-groups and minority groups, making it a must-readfor those who support young adults as they move from school to work. Written by internationally renowned scholars in developmental psychology, applied psychology, counseling, and sociology, the chapters in this book highlight the trends, issues, and actions that researchers, academics, practitioners, and policy makers need to consider in order to effectively support young adults' transition to work pathways. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

Zustand: New. In English.

Paperback. Zustand: New. The school-to-work transition is a critical part of the human life-span for young adults, their families, and society. The timing of the transition varies greatly and its co-occurrence with a number of other life transitions make it challenging to summarize or generalize. Individual differences and normative developmental factors, as well as external contextual factors such as global pandemics, changing economic circumstances, workplace demands, and cultural shifts, intersect to create a range of challenges and opportunities for those navigating this transition. Written by internationally renowned scholars in developmental psychology, applied psychology, counseling, and sociology, the chapters in this book highlight the trends, issues, and actions that researchers, academics, practitioners, and policy makers need to consider in order to effectively support young adults' transition to work pathways. This volume provides an explicitly international perspective on this area, broad coverage of psychological topics on the school-to-work transition, and an inclusive focus on sub-groups and minority groups, making it a must-read for those who support young adults as they move from school to work. …

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Paperback. Zustand: Brand New. 544 pages. 9.00x6.00x1.25 inches. In Stock.

Paperback. Zustand: New. The school-to-work transition is a critical part of the human life-span for young adults, their families, and society. The timing of the transition varies greatly and its co-occurrence with a number of other life transitions make it challenging to summarize or generalize. Individual differences and normative developmental factors, as well as external contextual factors such as global pandemics, changing economic circumstances, workplace demands, and cultural shifts, intersect to create a range of challenges and opportunities for those navigating this transition. Written by internationally renowned scholars in developmental psychology, applied psychology, counseling, and sociology, the chapters in this book highlight the trends, issues, and actions that researchers, academics, practitioners, and policy makers need to consider in order to effectively support young adults' transition to work pathways. This volume provides an explicitly international perspective on this area, broad coverage of psychological topics on the school-to-work transition, and an inclusive focus on sub-groups and minority groups, making it a must-read for those who support young adults as they move from school to work. …

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Paperback. Zustand: new. Paperback. The school-to-work transition is a critical part of the human life-span for young adults, their families, and society. The timing of the transition varies greatly and its co-occurrence with a number of other life transitions make it challenging to summarize or generalize. Individual differences and normative developmental factors, as well as external contextual factors such as global pandemics, changing economic circumstances, workplace demands, and cultural shifts,intersect to create a range of challenges and opportunities for those navigating this transition.Written by internationally renowned scholars in developmental psychology,applied psychology, counseling, and sociology, the chapters in this book highlight the trends, issues, and actions that researchers, academics, practitioners, and policy makers need to consider in order to effectively support young adults' transition to work pathways. This volume provides an explicitly international perspective on this area, broad coverage of psychological topics on the school-to-work transition, and an inclusive focus on sub-groups and minority groups, making it a must-readfor those who support young adults as they move from school to work. Written by internationally renowned scholars in developmental psychology, applied psychology, counseling, and sociology, the chapters in this book highlight the trends, issues, and actions that researchers, academics, practitioners, and policy makers need to consider in order to effectively support young adults' transition to work pathways. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

Zustand: New. Print on Demand pp. 544.

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The school-to-work transition is a critical part of the human life-span for young adults, their families, and society. The timing of the transition varies greatly and its co-occurrence with a number of other life transitions make it challenging to summarize or generalize. Individual differences and normative developmental factors, as well as external contextual factors such as global pandemics, changing economic circumstances, workplace demands, and cultural shifts, intersect to create a range of challenges and opportunities for those navigating this transition. Written by internationally renowned scholars in developmental psychology, applied psychology, counseling, and sociology, the chapters in this book highlight the trends, issues, and actions that researchers, academics, practitioners, and policy makers need to consider in order to effectively support young adults' transition to work pathways. This volume provides an explicitly international perspective on this area, broad coverage of psychological topics on the school-to-work transition, and an inclusive focus on sub-groups and minority groups, making it a must-read for those who support young adults as they move from school to work.…

Zustand: New. Print on Demand pp. 544.