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Softcover. Zustand: Neu. 70 S., 44 Abb., 40 Tab. Neu! - Versandfertig am nächsten Tag; Rechnung mit MwSt. liegt bei! In dem vorliegenden Buch werden ausführlich die pathologische Anatomie, die Klinik und die Diagnostik maligner Hodentumoren sowie die drei Therapiemodalitäten Operation, Radiotherapie und Chemotherapie abgehandelt. Günstige Gelegenheit. Sprache: Deutsch.…

Hardcover. Zustand: Gut. gebunden, 180 Seiten / guter Zustand Sprache: Deutsch Gewicht in Gramm: 520.

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XXXII,773 S. Broschur. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Deutsch.

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4. Aufl. Thieme, Stgt., 1993. XIII/671 S. mit 29 Abb. u. 97 Tabellen., kart.--- 550 Gramm.

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Hormonal treatment of malignant diseases has been used for quite some years now, and progress in this field is still being made at a steady pace. The detection of new endocrine feed back loops and the availability of new classes of hormonal agents made hormonal intervention with predictable outcome possible. Besides the intellectual challenge of modulating the hormone system, an important aspect of recent research on hormones and cancer is the reduction of treatment-related morbidity achieved with the new hormonal strategies. Thus, controlled intervention in the hypothalamic-gonadotropic axis is increasingly apt to replace surgical removal of the relevant glands, i. e. , the pituitary gland or the gonads. In the same way as, for example, aromatase inhibitors are being used as a substitute for adrenalectomy. The concept that secretion of hypothalamic gonadotropin releasing hormone (GnRH), pituitary gonadotropins, and sex steroids are regulated via negative and positive feedback loops is based on the pioneering work of Hohlweg and Harris some 40 years ago. In 1971, a breakthrough was achieved with the isolation, structural analysis, and synthesis of the luteinizing hormone releasing hormone (LH-RH), or GnRH as it is now more appropriately termed, since it provokes the secretion of both gonadotropins, LH and FSH, and since then the progress made in this area of research has been remarkable. Both ago nists and antagonists of LH-RH have been synthesized and extensively studied in preclinical and clinical settings.…

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San Francisco : Zuckschwerdt, 1989, 179 Seiten : 49 Ill. u. graph. Darst. ; 24 cm ; gebunden, illustriertes Hardcover ; sehr guter Zustand.

San Francisco : Zuckschwerdt, 1989, 179 Seiten : 49 Ill. u. graph. Darst. ; 24 cm ; gebunden, illustriertes Hardcover ; sehr guter Zustand, vorne ein Adressstempel.

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Zustand: New. pp. 112.

Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Interference with protein-mediated intra- and intercellular pathways has become a major goal of preclinical and clinical research. A ,rapidly increasing numBer of peptides are known to be responsible for endo-, para-and autocrine sig nal transduction. These peptides and their receptors have been studied with regard to their cell growth stimulatory ac tion and their impact on differentiation. In parallel, peptide antagonists are being investigated in terms of their potential role in preclinical and clinical application. Thus, biotherapy might improve the clinical outcome of patients with tumors that respond to the respective hormonal manipulation. Among the numerous peptides of interest somatostatin (somatotropin release inhibitory factor) and the luteinizing hormone releasing hormone (LH-RH) have been the topic of intensive research during recent years. In this third vol ume of peptides in oncology, experts in the field exten sively review and update the mechanisms of action of so matostatin and LH -RH -analogues in oncology. Somatostatin and its various short-and long-acting ana logues have the unique feature of suppressing and inhibit ing a wide range of cellular processes including cell prolif eration. Receptors for these peptides which belong to the family of neuropeptides or neurotransmitters, are widely distributed, a feature which is not in keeping with the gen eral view of a growth hormone regulatory system. LH -RH analogues play an established role in curative (adjuvant) and palliative treatment of hormone sensitive tumors.…