Umesh shiroya (6 Ergebnisse)

Taschenbuch. Zustand: Neu. In-silico design and synthetic studies of DNA-Gyrase inhibitors | Design, Synthesis and Anti-bacterial activity of 5,7-dihydroxy-4-methylcoumarin derivatives as DNA-gyrase inhibitors | Umesh Shiroya (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783848483075 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Paperback. Zustand: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Paperback. Zustand: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: PATEL SANJAYI have completed M.Pharm (Pharm. Chemistry) from Gujarat Technological University, Gujarat (India). Currently working as a Research Associate Scientist in Piramal Discovery Solutions. I have expertise in Drug designing & .…

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Shiroya UmeshI have got M.pharma (Pharmaceutical chemistry) degree from Gujarat Technological University in 2011.I have worked in different areas of Pharmaceutical field. I have published many research and review articles in reputed .…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Coumarins are important class of compounds, isomeric to quinolones. They may become promising candidates for exploiting more useful therapeutically active molecules. DNA-gyrase has drawn much attention as selected target for finding potent anti-bacterial agents against multi-drug resistant strains such as methicillin-resistant Staphyloccus aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-resistant Streptococci pneumonia (PRSP). The objective of the present study was, to study the molecular docking simulations on 5,7-dihydroxy-4-methyl coumarin analogues as probable candidates for inhibiting DNA gyrase subunit-B of S.aureus. In the present study, Docking simulations were carried out on the reported inhibitors of DNA-gyrase subunit A and B using docking software. Based on it, Series of 5,7-dihydroxy-4-methylcoumarin analogues (PH-1 to PH-9) were designed, synthesized, characterized and evaluated for its anti-bacterial activity against S.aureus and E.coli. Out of the nine test compounds, compound PH-4 showed good anti-bacterial activity against S.aureus and E.coli than rest of other compounds.…