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Taschenbuch. Zustand: Neu. Neuware - This volume presents the proceedings of the Second International Sym posium on Acoustical Holography, which was held at the Douglas Advanced Research Laboratories on 6 and 7 March 1969, fifteen months after the first symposium. Space was limited to about 110 seats, with representatives from nine countries attending. These countries included Canada, England, France, Japan, Mexico, Scotland, Sweden, Switzerland, and the United States. The symposium consisted of 21 formal papers. The twenty second, by Dr. U. Fehr, was not read, but is included in these proceedings. The manu script of the interesting paper on acoustic propagation in a turbulent medium which was read by Dr. O. K. Mawardi was not received in time for publication in these proceedings, and we look forward to its publication perhaps at a later date in the open literature. In addition to the formal papers there were three informal presentations at the end of the meeting which were given by Dr. A. Lohmann, by L. A. Cram and K. O. Rossiter, and by T. S. Graham, which are also included in these proceedings. At the end of the formal presentations Dr. Lewis Larmore summarized the symposium and discussed some of the highlights. For the symposium summary and a summary of these proceedings the reader is referred to Chapter 1.…

Taschenbuch. Zustand: Neu. Neuware - 1 Clinical and Molecular Genetics of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.- Introduction: Adrenal Steroidogenesis.- The Physiology of 21-Hydroxylase Deficiency.- Genetics of the 21-Hydroxylase Locus.- Southern Blotting Studies in CAH.- Gene Defects Detectable by Southern Blotting.- Point Mutations in CAH.- Prenatal Diagnosis of CAH.- References.- 2 Genetic Aspects of Amyloidosis.- Amyloidosis: Historical Background.- Amyloidosis: Definition.- Chemical Classification of the Amyloid Syndromes.- Transthyretin-Associated Amyloidosis.- Familial Mediterranean Fever and Other Hereditary Amyloidoses of the Amyloid A (AA) Type.- ACYS (Cystatin C) Hereditary Cerebral Hemorrhage with Amyloidosis: (HCHWA)-Iceland.- Aß Amyloidosis: Dutch-Type HCHWA, Alzheimer's Disease, and Down Syndrome.- AGEL: Familial Amyloidosis of the Finnish Type.- AAPOAI: Familial Amyloid Polyneuropathy, Iowa-(Van Allen).- AC AL: Multiple Endocrine Neoplasia.- Miscellaneous Hereditary Amyloidoses.- The Treatment of Hereditary Forms of Amyloidosis.- Conclusions.- References.- 3 Huntington's Disease.- Clinical Characteristics of HD.- Neuropathology and Neurochemistry.- Epidemiology.- A Molecular Genetic Approach to Investigation of HD.- Success of the Linkage Strategy.- Defining the HD Candidate Region.- Isolation of DNA Probes from the Candidate Region.- Fine Structure Physical Mapping of the Candidate Region.- Genetic Mapping of the Candidate Region.- Positioning of the HD Gene by Apparent Crossover Events.- Linkage Disequilibrium.- What Is the HD Gene .- References.- 4 Biochemical and Molecular Genetics of Cystic Fibrosis.- Early Attempts to Identify Biochemical Markers for CF.- Epithelial Ion Transport.- CF Gene Mapping.- Identification of the CF Gene.- The CF Gene Product(CFTR).- Genotype and Phenotype.- Explanations for High CF Gene Frequency.- Genetic Diagnosis.- Concluding Remarks.- References.- 5 Molecular Genetics of von Recklinghausen Neurofibromatosis.- Clinical Features.- Genetics of NF1.- Biochemical and Neurobiological Aspects.- Molecular Genetics.- Future Directions.- References.- Addenda. …

Taschenbuch. Zustand: Neu. Neuware - What have been brought together in these volumes are works represent ing a variety of modern quantitative studies on a select group of marine organisms. Some of the species studied here represent basic biological ex perimental subjects-in some cases, marine versions of the white rat and pigeon-that are being used for a wide range of studies. Other species studied were virtually unknown as experimental animals. The authors have studied their animals in considerable depth, often in both the field and the laboratory. It is this cross reference between real life and the artificial but controlled conditions of the laboratory which gives us the necessary understanding, and ultimately the means, for improving our rapidly deteriorating environment, a must for man's survival, maintenance, and improvement of the quality of living standards. A direct outgrowth of a AAAS symposium entitled 'Recent Advances in the Behavior of Marine Organisms' held in December 1966, these vol umes include a reasonable balance between review and original unpublished research. Of the many persons who have made these volumes possible, we wish to especially thank Nancy Fish, Lois Winn, Mabel Trafford, and Deborah Brennan. The latter two accomplished most of the final editorial work. The personnel of Plenum Press were cooperative in all aspects of our rela tionship. Only the two editors are responsible for defects in the volumes. We believe the papers presented are significant and will be of importance to members of the scientific community.…

Taschenbuch. Zustand: Neu. Neuware - Few advances in cardiovascular medicine have so captured the inter est of physicians and the public alike as has coronary artery bypass surgery. Cardiologists who lived through the era of false hopes and frustrations of previous' operations' for coronary artery disease can fully appreciate what this major advance offers to their patients. The number of papers on this topic presented at national meetings attest to its popularity, but also make it increasingly difficult for anyone to assimilate all the data. Practitioners who must consider coronary artery bypass surgery for their patients may thus have difficulty in coming to some rational decision regarding the indications for the operation and its consequences. Depending on the 'authority' that one reads, there is still some controversy as to which patients are candidates for coronary artery surgery. This monograph on the prac tice of coronary artery bypass surgery, therefore, comes as a welcome boon to cardiologists, surgeons, internists, and general practitioners who must consider referring their patients for such surgery. It presents a balanced and reasonable picture of the overall subject, in addition to containing important information on such topics as opera tive technique and economic impact. Dr. Miller has done an outstand ing job in bringing together in one text the important considerations related to the evaluation of patients, the natural history of coronary artery disease and the benefits and problems associated with bypass surgery.…

Taschenbuch. Zustand: Neu. Neuware - In the early 1960s, Dr. Alexander G. Karczmar, Professor of Pharmacology and Experimental Therapeutics at the Stritch School of Medicine of the Medical Center at Loyola University of Chicago, was confronted with a certain technical problem concerning his studies of synaptic transmission by means of microelectrode methods. He thought that the problem might be resolved if he could interest a microelectrode expert such as Dr. Kyozo Koketsu in his studies. Dr. Koketsu was a past member of the Faculty of the Kurume University School of Medicine who as a Research Fellow at the Australian National University had helped Sir John Eccles, subse quently a Nobel Prize winner, in developing microelectrode procedures. After further considering the matter, Dr. Karczmar was pleasantly sur prised to discover that by coincidence Dr. Koketsu was his neighbor, serving at that time as a Research Professor at the Neuropsychiatry Institute of the University of Illinois, College of Medicine of Chicago. This was the beginning of a long relationship, as Dr. Koketsu joined Dr. Karczmar at Loyola as Professor of Pharmacology and Therapeutics and Director of the Neurophysiology Laboratory at the Stritch School of Medicine. It was not long before Dr. Syogoro Nishi-Dr. Koketsu's former colleague on the Faculty of Medicine at Kurume University, and at that time a Research Fellow in Neurophysiology at the Rockefeller Institute in New York joined Drs. Koketsu and Karczmar at Loyola. Although in due time Drs.…

Taschenbuch. Zustand: Neu. Neuware - Computer vision is one of the most complex and computationally intensive problem. Like any other computationally intensive problems, parallel pro cessing has been suggested as an approach to solving the problems in com puter vision. Computer vision employs algorithms from a wide range of areas such as image and signal processing, advanced mathematics, graph theory, databases and artificial intelligence. Hence, not only are the comput ing requirements for solving vision problems tremendous but they also demand computers that are efficient to solve problems exhibiting vastly dif ferent characteristics. With recent advances in VLSI design technology, Single Instruction Multiple Data (SIMD) massively parallel computers have been proposed and built. However, such architectures have been shown to be useful for solving a very limited subset of the problems in vision. Specifically, algorithms from low level vision that involve computations closely mimicking the architec ture and require simple control and computations are suitable for massively parallel SIMD computers. An Integrated Vision System (IVS) involves com putations from low to high level vision to be executed in a systematic fashion and repeatedly. The interaction between computations and information dependent nature of the computations suggests that architectural require ments for computer vision systems can not be satisfied by massively parallel SIMD computers.…

Taschenbuch. Zustand: Neu. Neuware - The present volume contains the edited transcript of a Totts Gap Colloquium held May 19-21, 1980 sponsored by the Muscular Dystrophy Association. The aim of the colloquium was to bring into focus data relating to cell membranes that might contribute to understanding the pathogenic mechanism of Duchenne muscular dystrophy. A major impediment to progress in understanding the patho genesis of muscular dystrophy has been the failure, so far, to identify the basic genetic defect. Pending the identification of the genetic lesion in Duchenne dystrophy and, in view of scattered but persistent indications of a basic membrane disturbance, it seemed worthwhile to explore in open dialogue the current state of knowledge of membrane morphology and chemistry with an eye to possible leads for further investigation. The participants, drawn from a variety of interested disciplines, attempted to synthesize and reconcile their findings and to identify crucial areas of ignorance in need of exploration. For the most part they avoided specialized jargon and spoke in a language that could be understood by the rest of the group. Apart from providing a review of widely varying approaches to the study of the composition and behavior of cell membranes, the discussions brought together current think~g on strategies and approaches to the study of the pathogenesis of muscular dystrophy. Already the personal contacts made at the colloquium have led to new inter-institutional collabora tive investigations.…

Taschenbuch. Zustand: Neu. Neuware - To accomplish these objectives, the book is Body surface electrocardiographic mapping is not a new technique. It is one initially de divided into five sections. In Part I, the deve veloped many decades ago, but it has only lopment of electrocardiographic leads as well as recently matured into a powerful tool for surface mapping is viewed from an historical studying the cardiac electrical field. This book perspective. This is followed in Part II by a is intended to review, both critically and in review of the fundamental physiologic and detail, the applications of this unique method biophysical principles of electrocardiography in both clinical and experimental environments. and a discussion of basic mapping techniques. A comprehensive description of reported re Applications of these methods to the normal sults is, however, only a first goal. An equally and the abnormal heart are then presented in important objective is to explore the elec Parts III and IV, respectively. Finally, the trophysiologic and biophysical bases for the work concludes (Part V) with a consideration empirically observed electrocardiographic pat of possible future directions that body surface terns. It is only after considering these basic mapping may follow. The final result is, hope foundations that the values and the limitations fully, a thorough statement defining the cur of any electrocardiographic method can be rent s~atus of body surface electrocardiographic understood. This is particularly true for body mappmg.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the Proceedings of the NATO Advanced Research Workshop on 'Growth and Optical Properties of Wide Gap II-VI Low Dimensional Semiconductors', held from 2 - 6 August 1988 in Regensburg, Federal Republic of Germany, under the auspices of the NATO International Scientific Exchange Programme. Semiconducting compounds formed by combining an element from column II of the periodic table with an element from column VI (so called II-VI Semiconductors) have long promised many optoelectronic devices operating in the visible region of the spectrum. However, these materials have encountered numerous problems including: large number of defects and difficulties in obtaining p- and n-type doping. Advances in new methods of material preparation may hold the key to unlocking the unfulfilled promises. During the workshop a full session was taken up covering the prospects for wide-gap II-VI Semiconductor devices, particularly light emitting ones. The growth of bulk materials was reviewed with the view of considering II-VI substrates for the novel epitaxial techniques such as MOCVD, MBE, ALE, MOMBE and ALE-MBE. The controlled introduction of impurities during non-equilibrium growth to provide control of the doping type and conductivity was emphasized. 364 pp. Englisch. …

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When the present symposium was first conceived, it was decided that more emphasis be given to contributions from biological laboratories than has typically appeared in previous bionics meetings. Accordingly, most of the invited speakers are biologists, in the broad sense of representing some area of the life sciences. Likewise, many of the submitted papers eventually chosen by the technical com mittee were from the life sCiences, rather than the physical sciences or mathe matics. In this way, it was hoped that a greater direct interest in the technological problems of bionics might be stimulated among biologists, upon whose work much of the success of bionics necessarily lies. Because of the wide interdisciplinary span of the papers, it was necessary to impose some artificial organization upon them, specifically for continuity in the transactions. We elected to put the biological papers first, followed by those which deal with reasonably specific models, and reserveto the last those papers reporting models which are more general in nature. The editorial function was kept to a minimum, with no major alterations of content and few of style being exercised. Several of the papers delivered at the symposium required a longer format for clarity and are included here in ex panded versions. Assitance in the preparation of this volume was received from the National Institute of Neurologic Diseases and Blindness, Grant number B-3896. 412 pp. Englisch. …

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is devoted to the chemistry, immunology, molecular biology, and physiology of the human chorionic gonadotropin, heG. For this glycoprotein molecule the course from discovery to chemical deciphering covered about fifty years. It was in 1928 that Ascheim and Zondek reported that urine from pregnant women contains something that stimulates the ovaries of mice or rats. This provided the basis for the famous A-Z test for pregnancy and for the 'rabbit test' modification introduced by Friedman. As researchers sought to find more sensitive responses to heG, they used a wide variety of species including the South African aquatic toad, Xenopus Zaevis, the terrestrial toad of South America, Bufo arinarus, and the African weaver finch, EupZeetes afra. The weaver finch feather reaction was particularly noteworthy, for it disclosed a non-gonadal response to heG/LH. In retrospect, this may have been an important evolutionary clue to the realization that the designation of the hormone as a 'gonadotropin' may have been only partially descriptive of the molecule's physiological function--a concept that is gaining attention, as the papers in this 1980 volume divulge. 520 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the last few centuries, and particularly in recent decades, problems result ing from the excessive use of drugs and alcohol have spread virtually as an epidemic to every country in the world and to almost every community. Abuse of alcohol and drugs is related to numerous other health problems, such as the spread of acquired immune deficiency syndrome (AIDS) on all continents. Health and social services today cannot afford to ignore this crisis since it affects all levels of society and manifests itself in diverse health and social problems. In recent years, the World Health Organization has received numerous requests for training material for physicians in this field. This manual therefore meets an urgent need. The availability of new data and the dearth of suitable textbooks have made its preparation mandatory. The influence of sociocultural factors on drug dependence and alcohol related problems-on their cause, development, and consequences as well as on their treatment and prevention-has been taken into account in the preparation of this manual in order to ensure that its usefulness is not limited to one country or region. It has been prepared primarily for the teaching of physicians and medical students, although much of it is relevant to the training of nurses, midwives, health educators, primary-care workers, medical social workers, counselors, and psychologists. In fact, suggestions have been included for adapting the manual for use in the training of such varied groups of students. 352 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the invited lectures presented in a symposium entitled 'Evolutionary strategies of parasitic insects and mites' at the national meeting of the Entomological Society of America in Minneapolis, Minnesota, 2-5 December, 1974. The intent was to bring together biologists who have worked on arthropods that are either plant or animal parasites in order to foster consideration of general aspects of the parasitic way of life. There seems to be a deficiency of ecological and evolutionary concepts relating to parasitism, in contrast to the burgeoning literature on predation, and it appeared that an amalgamation of studies on plant and animal parasites might help development of some generalities. Since parasities are far more numerous than predators in the world fauna, or in any particular community, emphasis on their study is justified. I freely admit that para sitoids have been usefully regarded as predators by ecologists, and many concepts on predation have been derived from their study. Also, in whichever category one places the parasitoids, that is the one which contains the most species. However, from an evolu tionary point of view they show many characteristics that must be regarded as those of a parasite. Notably, they are small, highly specific to their host, highly coevolved with it, as a result many species can coexist, and their adaptive radiation has produced the majority of the species diversity seen on Earth today. 240 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume records the proceedings of, and the papers read at, an international conference to consider the use of electronic data processing methods in the major taxonomic plant collections of Europe, primarily herbaria but also living collections. This conference took place at the Royal Botanic Gardens, Kew, from 3rd to 6th October, 1973. It was attended by some 90 delegates, observers and speakers, mainly from a wide range of the major European herbaria, but also from other interested institutions. The problem to be discussed was a big one. Taxonomic collections of the sorts mentioned above constitute the main centres for the scientific documentation of the flora of the world. With the extinction of so many species more or less imminently threatened, and with the modification or disappearance of so many vegetation types through the activities of man, the information contained in these collections grows in importance. Their aggregate size, in Europe, has been estimated at between 50 and 100 millions, and these are annually augmented at a rapid rate. Each specimen or living plant comprises a source of evidence and information represented both by the specimen itself and the associated information provided by the collector and subsequent investigators - identifications, field notes, records of subsequent research, etc. This associated information is known as the label data. Research on the taxonomy and geographical distribution of plants usually requires data from specimens stored in a number of institutions in different countries. 228 pp. Englisch. …

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Editors are sorry that the production of this volume was delayed by the ill health of one of them and we hope that this does not detract from the value of the con tents. For once this delay is not the fault of any of the authors only the editors are to blame. Many of the workers in the field of fibre toxicology became convinced by the middle 1980's that the worst of the furore over asbestos was over although we were left with an intriguing problem - how does asbestos cause disease It was expected that the future impact of fibres on human health would be very small since asbestos exposure would be controlled and there was little chance that man-made fibres would prove haz ardous. These man-made fibres are much thicker than asbestos and, in most cases, they are less durable in the body. Both of these properties are believed to make them much less likely to cause disease. However many of us had fallen into the habit of calling these materials 'asbestos substitutes' and thus they have acquired a little of the notoriety at tached to the natural fibrous minerals. Very few of these man-made fibres are actually used as replacements for asbestos. Asbestos was not suitable for the uses to which the insulation wools are usually put and the ceramic fibres are replacements for fire brick not asbestos which is destroyed at the temperatures at which these materials are used. 608 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book, written by the eminent Russian organic chemist Professor M. G. Voronkov, exhaustively deals with the reactions of sulfur with organic compounds. It is the only book on the subject which covers both work readily available to Western scientists and research carried out by Russian workers. Since much of the work discussed in this volume is not readily accessible to Western scien tists, it will enable them to find hitherto 'unpublished' research. In addition, Professor Voronkov has dealt with many reactions and processes of interest to the industrial chemist; e.g., there is an interesting section on sulfur dyes and related compounds, and the chemistry of vulcanization is lucidly discussed. Hence this book should be of value to both academic and industrial chemists inter ested in the chemistry and reactions of sulfur, and also to those synthetic chemists studying new pathways to organic compounds. The text has recently been updated and revised, and there are numerous references to publications up to and including 1980. An exhaustive index is provided to enable the reader to refer rapidly to any of the compounds, reactions, or processes discussed in the text. 444 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In many areas of physics, such as astrophysics, solid-state physics, nuclear physics and particle physics, a major outstanding problem is a better understanding of corre lation phenomena. While in most cases the average properties of a system are rather well understood, the correlations and the resulting clustering are poorly understood. They are reflections of the force mediating the interaction among the constituents and play essential roles in determining the structure of a physical system. At the largest scales, in astrophysics, it has recently been realized that there are huge voids in space and almost all matter is concentrated on filaments, raising interesting questions concerning the origin of this clustering of matter. In nuclear physics corre lation phenomena are important in all its subfields. It has been realized that so-called fluctuations in the one-particle density, which are a manifestation of nucleon-nucleon correlations, are crucial. These are important for an understanding of heavy-ion reac tions. This is the subject of modern quantum transport theories. Correlations are also crucial in the description of the high momentum components as observed in quasi-elastic knock-out reactions. 280 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As a result of the industrial revolution, man's technological achievements have been truly great, increasing the quality of life to almost unimagined proportions; but all this progress has not been accomplished without equally un imagined health risks. Sufficiently diagnostic short-term assay procedures have been developed in recent years for us to determine that there are mutagenic agents among thou sands of chemicals to which the human population is exposed today. These chemicals were not significantly present prior to the indus trial revolution. As of today, there are no procedures available which have been adequately demonstrated to assess individual sus ceptibility to genotoxic exposures, and as a result we have had to rely on extrapolating toxicological data from animal model systems. The question is can we afford to allow such an increased environ mental selection pressure via mutagenic exposures to occur without expecting adverse long-term effects on our health. It is apparent from this line of reasoning that what is lacking and immediately needed are test procedures that can be applied to humans to assess genotoxic exposure as well as individual susceptibility to it. There have already been two conferences which have focused at tention on this research area. 'Guidelines for studies of human populations exposed to mutagenic and reproductive hazards' (A. D. Bloom, ed., March of Dimes Birth Defects Foundation, White Plains, New York, 1981) and 'Indicators of genotoxic exposure in humans' (Banbury Report 13, B. A. Bridges, B. E. Butterworth, and I. B. 532 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This century has witnessed the creation of new sciences extending the frontiers of knowledge to an unprecedented degree. We have seen the birth of cybernetics and bionics, bringing together such apparently distantly related branches of science as neurohistology and automation, synaptology and electronics. The electron microscope has resolved tissues almost down to the molecular level, and histochemistry has led to the fine analysis of brain structure. However, before these and other new sciences can develop properly and scientifically, a precise knowledge of the structure of the material with which they are concerned is absolutely essential. That is why the need exists at the present time for a detailed study of the larger units, i. e. , the neurons, their interrelationships and the pathways by which excitation is conducted. Biologists, neurologists, physicists, and specialists in other technical disci plines will find this study highly useful. During recent years many advances have been made in knowledge of the central visual system and its pathways. Above all, it has been found that the visual system is very extensive. The optic tract is connected, not only with the lateral geniculate body, but with the superior colliculus and the pulvinar. Besides the discovery of these principal pathways, connections have also been studied with the hypothalamus, the pretectal region, the medial geniculate body, subthalamus, and other parts of the brain stem. The visual system is thus connected with the reflex apparatus, the autonomic nervous system, and the auditory and reticular systems. 304 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The intention of this monograph has been to assimilate key practical and theoretical aspects of those spectroelectrochemical techniques likely to become routine aids to electrochemical research and analysis. Many new methods for interphasial studies have been and are being developed. Accordingly, this book is restricted in scope primarily to in situ methods for studying metal! electrolyte or semiconductor! electrolyte systems; moreover, it is far from inclusive of the spectroelectrochemical techniques that have been devised. However, it is hoped that the practical descriptions provided are sufficiently explicit to encourage and enable the newcomer to establish the experimental facilities needed for a particular problem. The chapters in this text have been written by international authorities in their particular specialties. Each chapter is broadly organized to review the origins and historical background of the field, to provide sufficiently detailed theory for graduate student comprehension, to describe the practical design and experimental methodology, and to detail some representative application examples. Since publication of Volume 9 of the Advances in Electrochemistry and Electrochemical Engineering series (1973), a volume devoted specifically to spectroelectrochemistry, there has been unabated growth of these fields. A number of international symposia-such as those held at Snowmass, Colorado, in 1978, the proceedings of which were published by North-Holland (1980); at Logan, Utah in 1982, published by Elsevier (1983); or at the Fritz Haber Institute in 1986-have served as forums for the discussion of nontraditional methods to study interphases and as means for the dissemination of a diversity of specialist research papers. 468 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the time of the discovery of the fission of the nucleus, when Hahn and Strassmann first detected the products of nuclear fission in 1939 in uranium irradiated by neutrons, over two decades have passed. In the work accom plished since that time, research has been greatly expanded on fission products and has been extended to many nuclides formed in the fission of various nu clei induced by neutrons, gamma rays, charged particles, and in spontaneous fission. Amassing of experimental results is an important task not only for nu clear engineering but also for an understanding of the fission process itself, for bringing into existence a finished theory on the unique and intriguing physi cal phenomenon which plays such a decisive role in the practical utilization of nuclear energy. In this reference manual, an attempt is made to collect and generalize upon the results of experimental research work over the period spanning 1939 to 1962, on yields of fission products and on the mass distribution of fission fragments. Various instances of the fission of nuclei induced by neutrons, gamma rays, charged particles, and spontaneous fission of nuclei are discussed. 132 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Permanent Commission and International Association on Occupational Health (PCIAOH) established in 1969 a Subcommittee on the Toxicology of Metals under the chairmanship of Lars Friberg. This committee, which later was named the Scientific Committee on the Toxicology of Metals, has organized a number of previous meetings that have led to publications in three major areas of metal toxicology: a preliminary meeting in Slanchev Bryag, Bulgaria in- 1971, followed by a meeting in 1972 in Buenos Aires, Argentina which produced two reports (Dukes and Friberg, 1971; Task Group on Metal Accumulation, 1973), that discussed the metabolism of metals with special reference to absorption, excretion and biological half-times. The effects and dose-response relationships of toxic metals, including a discussion of general principles, was the second major topic addressed by the Scientific Committee at a meeting in Tokyo in 1974 (Nordberg, 1976). The philosophy of this conference, as well as the previous one in Buenos Aires, was based on the concept of a 'threshold dose' for the occurrence of adverse effects. In a conference held in Atlanta, USA in 1980, the scope of discussion on metal effects was broadened to include the role of metals in carcinogenesis. Thus, for the first time, the Scientific Committee took under consideration the possibility of non-threshold relationships (Belman and Nordberg, 1981). In addition, the Scientific Committee on the Toxicology of Metals organized a workshop on metal interactions in Stockholm 1977 (Nordberg et al. 864 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thus far in the history of biology, two, and only two, fundamental principles have come to light that pervade and unify the entire science-the cell theory and the concept of evolution. While it is true that recently opened fields of inves tigation have given rise to several generalizations of wide impact, such as the universality of DNA and the energetic dynamics of ecology, closer inspection reveals them to be part and parcel of either of the first two mentioned. Because in the final analysis energy can act upon an organism solely at the cellular level, its effects may be perceived basically to represent one facet of cell me tabolism. Similarly, because the DNA theory centers upon the means by which cells build proteins and reproduce themselves, it too proves to be only one more, even though an exciting, aspect of the cell theory. In fact, if the matter is given closer scrutiny, evolution itself can be viewed as being a fundamental portion of the cell concept, for its effects arise only as a consequence of changes in the cell's genetic apparatus accumulating over geological time. Or, if one wishes, the diametrically opposite standpoint may be taken. For, if current concepts of the origin of life hold any validity, the evolution of precellular organisms from the primordial biochemicals must have proceeded over many eons of time prior to the advent of even the most primitive cell. 720 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -tematic description of the present problems of the physics of plasticity and strength, and to a certain extent is meant to fill the gap in the Russian litera ture on these problems. \* This collection contains articles devoted to the plastic properties of monocrystals and one article devoted to the description of the latest views and experimental data on the structure and properties of grain boundaries. The first four articles concern some problems of the plastic properties of one crystal grain (crystallite). The last article is a review of the basic studies of the mosaic (block) structure of monocrystals and grains of polycrystals, and also the structures and properties of interlayers between grains and aggre gates. t Almost all the articles of this collection contain results of original in vestigations by the authors of the articles and the basic conclusions are based on original data as well as da ta in the litera ture. 204 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The articles which make up this book were all expressly written to honor a remarkable man and a remarkable psychologist, Joseph McVicker Hunt, on the occasion of his 70th birthday. The contributors to this volume, with the exception of Hunt's teacher, J. P. Guilford, are students and colleagues of Hunt's whose intellectual and professional paths have crossed his in some significant way. In terms of content, the contributions collectively range across many of the conventional boundaries that demarcate the territories into which psy chological subject-matter has been divided. In so doing, they remain faithful to the man they honor, for whom such boundaries have had, at best, only provisional reality. Yet as the introductory chapter attempts to make clear, there is a unifying theme that lies behind the apparent diversity of Hunt's work. While we wished to mark Hunt's specific contributions to the diverse areas represented in this book, we also hoped to capture the unity of viewpoint that ties them together. 464 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The use of computer-aided design (CAD) systems always involves the introduction of mathematical concepts. It is important, therefore, for any systems designer to have a good grasp of the mathematical bases used in CAD. The choice of mathematical models in a system also has an effect on the overall quality, although this effect may not always be visible to the final user. Depending on whether Bezier or B-spline functions are used for curves and surfaces, for example, the final user even if not a com puter scientist will notice a difference. If, for example, one of the control points is modified by the user, in a Bezier-type representation, the curve or surface will tend to be modified overall, but in a B-spline representation, the curve or surface will tend to be modified close to the point, and there only. More possibly harmful, however, is the effect of the mathematical model which has a number of properties invisible and unknown to the final user. In every case a model must be chosen with, it is hoped, the most appropriate characteristics and limits for the task in hand. 168 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book deals with the underlying theory and practical aspects of pressure gauges that are at present in general use. Because of the ever-increasing demands to provide a wider range of sophisticated and reliable vacuum equipment a good understanding of these instruments is of vital importance to all workers in the research and industrial sectors. Of the gauges considered only the mechanical types are absolute, in the sense that they measure pressure directly as a force upon a liquid column or a solid surface. Under ideal conditions it is possible to calculate their sensitiv ities, which are the same for all gases and vapours. The recent developments in the viscous or molecular damping gauges indicate that these may also be considered absolute. Other gauges are indirect in that they involve the measurement of some secondary phenomenon which is pressure-dependent and therefore these gauges can only be used for measurement after calibration against an absolute standard. The radiometer or Knudsen type gauge has been excluded from the text since these are now only of historic interest. Also no mention is made of the integration techniques involving surface changes (such as work function) although these could have application under very special circumstances. The McLeod gauge is dealt with in some detail, for even though this gauge has few practical applications, it is the most sensitive absolute gauge available and has value as a reference standard. 212 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The discovery of new molecules that function in neuronal communication can be viewed as a progression of steps beginning with the identification of the molecular structure, moving to the understanding of the mecha nisms mediating the synaptic action, and to the appraisal of the involve ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule's role in brain function and the consequences that are triggered by its abnormalities. Enkephalins have followed such a pattern, and the present publication expresses the salient points of the last two phases in this succession. Enkephalins were discovered in December 1975; in addition to pain threshold regulation, their participation in other brain functions was soon ascertained. Perhaps, there are multiple recognition sites for multiple molecular forms of endogenous enkephalins; similarly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to abnormalities in enkephalin storage, release, and synthesis. However, since our basic understanding of enkephalins is incomplete, the views reported should be considered to be in a state of flux. 512 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Knowledge Services Management looks at the transformation of the traditional workplace into a quasi-internal market environment where work activities in knowledge services are organized around clusters of similar or complementary knowledge stocks to address particular types of customer-clients priorities. The book explores a new internal market structure for these service organizations and the implications this presents for managers and scholars in the 21st century workplace. By adopting an internal market perspective, the book develops new organizational forms outside the traditional hierarchical paradigm, which is ill-suited for the emerging knowledge workplace, in order to effectively manage emerging knowledge services. The indispensable role of customer/client in the operations of these organizations is examined, as is the creation of the 'Proventure Workplace', a work environment which accentuates jobs requiring rich cognitive skills for continuing innovation and creativity. 200 pp. Englisch.…

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -He who knows and knows that he knows is wise; follow him. -ANCIENT PROVERB During a long career of public service as a government procurement and contracting official, I am still surprised to find big, successful corporations making the same mistakes that neophytes in government contracting mak~. And this is particularly true in the matter of writing proposals, which are the crucial element in most major procurement awards. It's true enough, as many suspect, that the big, well-known company has something of an edge over the smaller, lesser-known company com peting for any given government contract-psychologically, at least: The typical government executives, whether contracting officials or program managers, tend to have a bit more faith in the ability of the large company to carry out the program successfully. All things being equal, then, the big company is more likely to get the nod. However, because the large companies are well aware of that, many tend to become 'fat, dumb, and happy'-they try to coast or rest on their laurels. That is, they get careless about making a strong enough case for themselves in writing their proposals. And when they lose, often to smaller companies, they are both puzzled and outraged. They have for gotten that all government procurement is a competition-usually both technical and cost competition-and that the 'little guy' can win against the 'big guy,' if he tries hard enough. And especially if the bigger guy is a bit careless and does not put out his best effort. 308 pp. Englisch. …